Dec+9

Bell Ringer: Read the following http://www.suite101.com/content/preventing-deaths-in--student-athletes-with-the-sickle-cell-trait-a283827

Check out: http://sickle.bwh.harvard.edu/scd_background.html

How does sickle cell cause disease?

What causes sickle cells? The abnormal valine amino acid at position 6 in the beta globin chain interacts weakly with the beta globin chain in an adjacent sickle hemoglobin molecule. The complex twisting, 14-strand structure of the bundles produces multiple interactions and cross-interactions between molecules.

http://www.dnalc.org/view/15498-Hemoglobin-and-sickle-cell-anemia-3D-animation-with-no-audio.html = = =Homework: Circle the R-groups on the 20 amino acids handout. Due: 12/13 by 3:00=